external-validation

AI-powered chest X-ray pneumonia detection with 86% accuracy and 96.4% sensitivity, validated on an independent (cross-operator) cohort of 485 pediatric samples. Built with TensorFlow & FastAPI.

预测模型自学教程：从数据清洗到模型外部验证（R 语言）

Reproducible TCGA-LUAD survival pipeline on RNA-seq, clinical and mutation data. LASSO-Cox gene signature overfit (train C=0.722, test 0.538), reported as a negative finding; clinical Cox model (age, sex, grouped stage) validated on external cohort GSE31210 (C=0.708). Snakemake, Docker, FastAPI.

Developed ML algorisms on transcriptomics landscapes identi-fies SPON1 and ALDH1A2 as candidate prognostic biomarkers in TME and serous ovarian cancer progression

Reproducible regulatory transfer analysis for CRISPR interference in primary human CD4 T cells

Interpretable TCGA-BRCA RNA-seq breast cancer subtype classification with ML, SHAP, pathway enrichment, and METABRIC external validation.

Physiology-informed ICU sepsis early-warning model (LightGBM) trained on one hospital system and externally validated on another, with calibration, subgroup analysis and SHAP interpretation.

Designed and validated a computational oncology pipeline for hepatocellular carcinoma using RNA expression data, integrating machine learning, survival analysis, SHAP explainability, tumor microenvironment deconvolution, and multi-cohort external validation for precision medicine applications.

혈액 DNA 메틸화 8개 코호트(5,541명)로 학습한 연령 예측 Elastic Net. 코호트 단위 중첩 교차검증과 잠금 외부 검증(GSE87571 729명, MAE 2.80년)으로 누수 없는 일반화를 검증합니다.

Reproducible analysis notebooks for self-report–wearable measurement discrepancies, perceived stress, and external validation using Samsung Health and Fitbit datasets.

Predictions-only calibration validation for binary clinical prediction models: cluster-aware, cross-fitted, report-emitting. Python.

Biomedical abstract sentence classification workflow with calibration and external validation

Independent, reproducible evaluation of diagnostic and predictive-ML classifiers from model outputs and labels only. Standard-library Python. Implements the published METH-0.2 method.

Reproducible pipeline for development and external validation of an early distant recurrence model in stage III colon cancer.

Heart disease prediction tested at a hospital the model never saw: leave-one-site-out AUROC, calibration, and conformal prediction sets on the 4-site UCI data

Benchmark honesto de descriptores de imagen para clasificar lesiones cutaneas dermatoscopicas (ISIC): 390 combinaciones descriptor x algoritmo, control del efecto de lote y validacion externa entre instituciones. AUC 0.741 fuera del archivo de entrenamiento.

Independent external validation, recalibration & fairness audit of EchoNext-Mini (AI-ECG for structural heart disease) in MIMIC-IV

An evidence-driven weekly planning Skill that limits preparation and prompts early external validation.

Reproducibility code, processed data, out-of-fold predictions, and machine-readable results for leakage-aware e-commerce product classification using Mercadona and Amazon Reviews 2023.

Reserved-hospital evaluation of domain shift, calibration, and operating-point transportability in histopathology.