diff --git a/rclcpp/src/rclcpp/subscription_base.cpp b/rclcpp/src/rclcpp/subscription_base.cpp
index 2ea4664f52..4a9ce761b2 100644
--- a/rclcpp/src/rclcpp/subscription_base.cpp
+++ b/rclcpp/src/rclcpp/subscription_base.cpp
@@ -99,6 +99,23 @@ SubscriptionBase::SubscriptionBase(
 
 SubscriptionBase::~SubscriptionBase()
 {
+  // The middleware may be invoking this callback from one of its own threads.
+  // Unregister it before rcl_subscription_fini tears down the RMW subscription.
+  try {
+    clear_on_new_message_callback();
+  } catch (const std::exception & exception) {
+    RCLCPP_ERROR_STREAM(
+      node_logger_,
+      "rclcpp::SubscriptionBase@" << this <<
+        " failed to clear the on new message callback during destruction: " <<
+        exception.what());
+  } catch (...) {
+    RCLCPP_ERROR_STREAM(
+      node_logger_,
+      "rclcpp::SubscriptionBase@" << this <<
+        " failed to clear the on new message callback during destruction");
+  }
+
   if (!use_intra_process_) {
     return;
   }
diff --git a/rclcpp/test/rclcpp/test_subscription.cpp b/rclcpp/test/rclcpp/test_subscription.cpp
index fb7a57a1f7..360f726134 100644
--- a/rclcpp/test/rclcpp/test_subscription.cpp
+++ b/rclcpp/test/rclcpp/test_subscription.cpp
@@ -316,6 +316,39 @@ TEST_F(TestSubscription, rcl_subscription_fini_error) {
     node_->create_subscription<test_msgs::msg::Empty>("topic", 10, callback).reset());
 }
 
+TEST_F(TestSubscription, on_new_message_callback_cleared_before_fini) {
+  initialize(rclcpp::NodeOptions().use_intra_process_comms(false));
+  using test_msgs::msg::Empty;
+
+  bool callback_registered = false;
+  auto mock = mocking_utils::patch(
+    "lib:rclcpp", rcl_subscription_set_on_new_message_callback,
+    [&callback_registered](
+      const rcl_subscription_t *, rcl_event_callback_t callback, const void * user_data)
+    {
+      (void)user_data;
+      callback_registered = callback != nullptr;
+      return RCL_RET_OK;
+    });
+
+  auto sub = node_->create_subscription<Empty>(
+    "topic", 10, [](Empty::ConstSharedPtr) {});
+  sub->set_on_new_message_callback([](size_t) {});
+  ASSERT_TRUE(callback_registered);
+
+  auto fini_mock = mocking_utils::patch(
+    "lib:rclcpp", rcl_subscription_fini,
+    [&callback_registered](rcl_subscription_t *, rcl_node_t *)
+    {
+      EXPECT_FALSE(callback_registered);
+      return RCL_RET_OK;
+    });
+
+  sub.reset();
+
+  EXPECT_FALSE(callback_registered);
+}
+
 TEST_F(TestSubscription, rcl_subscription_get_actual_qos_error) {
   initialize();
   auto callback = [](std::shared_ptr<const test_msgs::msg::Empty>) {};