diff --git a/src/prompt_toolkit/widgets/menus.py b/src/prompt_toolkit/widgets/menus.py
index 9cb5de2bd..fbc490ae7 100644
--- a/src/prompt_toolkit/widgets/menus.py
+++ b/src/prompt_toolkit/widgets/menus.py
@@ -147,7 +147,7 @@ def _down_in_submenu(event: E) -> None:
         def _click(event: E) -> None:
             "Click the selected menu item."
             item = self._get_menu(len(self.selected_menu) - 1)
-            if item.handler:
+            if item.handler and not item.disabled:
                 event.app.layout.focus_last()
                 item.handler()
 
diff --git a/tests/test_widgets.py b/tests/test_widgets.py
index ee7745a2d..46abb3c2e 100644
--- a/tests/test_widgets.py
+++ b/tests/test_widgets.py
@@ -1,8 +1,16 @@
 from __future__ import annotations
 
+import pytest
+
+from prompt_toolkit.application import Application
+from prompt_toolkit.application.current import set_app
 from prompt_toolkit.formatted_text import fragment_list_to_text
-from prompt_toolkit.layout import to_window
-from prompt_toolkit.widgets import Button
+from prompt_toolkit.input import DummyInput
+from prompt_toolkit.key_binding.key_processor import KeyPress
+from prompt_toolkit.keys import Keys
+from prompt_toolkit.layout import Layout, to_window
+from prompt_toolkit.output import DummyOutput
+from prompt_toolkit.widgets import Button, MenuContainer, MenuItem, TextArea
 
 
 def _to_text(button: Button) -> str:
@@ -18,3 +26,63 @@ def test_default_button():
 def test_custom_button():
     button = Button("Exit", left_symbol="[", right_symbol="]")
     assert _to_text(button) == "[   Exit   ]"
+
+
+@pytest.mark.parametrize("disabled", [False, True])
+@pytest.mark.parametrize("depth", [0, 1, 2])
+def test_menu_keyboard_activation_respects_disabled(disabled, depth):
+    calls = []
+    item = MenuItem("Action", handler=lambda: calls.append(True), disabled=disabled)
+    menu_items = [item]
+    for _ in range(depth):
+        menu_items = [MenuItem("Submenu", children=menu_items)]
+
+    body = TextArea()
+    menu = MenuContainer(body=body, menu_items=menu_items)
+    app = Application(
+        layout=Layout(menu, focused_element=body),
+        input=DummyInput(),
+        output=DummyOutput(),
+    )
+    # These complete key sequences do not need an asynchronous timeout.
+    app.timeoutlen = None
+    app.layout.focus(menu.window)
+
+    navigation = [] if depth == 0 else [Keys.Down] + [Keys.Right] * (depth - 1)
+    with set_app(app):
+        for key in [*navigation, Keys.ControlM]:
+            app.key_processor.feed(KeyPress(key))
+            app.key_processor.process_keys()
+
+    assert calls == ([] if disabled else [True])
+    assert app.layout.has_focus(menu.window if disabled else body)
+
+
+def test_menu_keyboard_activation_checks_current_disabled_state():
+    calls = []
+    item = MenuItem("Action", handler=lambda: calls.append(True))
+    body = TextArea()
+    menu = MenuContainer(body=body, menu_items=[MenuItem("File", children=[item])])
+    app = Application(
+        layout=Layout(menu, focused_element=body),
+        input=DummyInput(),
+        output=DummyOutput(),
+    )
+    app.timeoutlen = None
+    app.layout.focus(menu.window)
+
+    with set_app(app):
+        app.key_processor.feed(KeyPress(Keys.Down))
+        app.key_processor.process_keys()
+
+        item.disabled = True
+        app.key_processor.feed(KeyPress(Keys.ControlM))
+        app.key_processor.process_keys()
+        assert calls == []
+        assert app.layout.has_focus(menu.window)
+
+        item.disabled = False
+        app.key_processor.feed(KeyPress(Keys.ControlM))
+        app.key_processor.process_keys()
+        assert calls == [True]
+        assert app.layout.has_focus(body)