diff --git a/web/config.py b/web/config.py
index f39c6085198..b96732a159a 100644
--- a/web/config.py
+++ b/web/config.py
@@ -144,8 +144,29 @@
 # such as JavaScript, CSS, or pretty much anything that the browser loads.
 # see https://content-security-policy.com/#source_list for more info
 # e.g. "default-src https: data: 'unsafe-inline' 'unsafe-eval';"
-CONTENT_SECURITY_POLICY = "default-src ws: http: data: blob: 'unsafe-inline'" \
-                          " 'unsafe-eval';"
+#
+# A per-request nonce is used in place of 'unsafe-inline' for scripts. The
+# literal token {nonce} anywhere in the policy is replaced at runtime with a
+# freshly generated nonce that is also emitted on pgAdmin's inline <script>
+# tags. To go back to the old permissive policy, set:
+#   CONTENT_SECURITY_POLICY = "default-src ws: http: data: blob:" \
+#                             " 'unsafe-inline' 'unsafe-eval';"
+# Notes:
+#  - 'unsafe-inline' is retained for style-src because pgAdmin's UI (React/MUI)
+#    injects styles at runtime that are not nonce tagged.
+#  - 'unsafe-eval' is NOT listed: production bundles do not need it.
+#    Development webpack bundles are built with the 'eval' devtool and DO
+#    need it, so when running the dev server add it in config_local.py, e.g.:
+#       CONTENT_SECURITY_POLICY = (
+#           "default-src 'self' ws: http: data: blob:;"
+#           " script-src 'self' 'nonce-{nonce}' 'unsafe-eval';"
+#           " style-src 'self' 'unsafe-inline';"
+#       )
+CONTENT_SECURITY_POLICY = (
+    "default-src 'self' ws: http: data: blob:;"
+    " script-src 'self' 'nonce-{nonce}';"
+    " style-src 'self' 'unsafe-inline';"
+)
 
 # STRICT_TRANSPORT_SECURITY_ENABLED when set to True will set the
 # Strict-Transport-Security header
diff --git a/web/pgadmin/__init__.py b/web/pgadmin/__init__.py
index 66902dfaabd..fa943ba5158 100644
--- a/web/pgadmin/__init__.py
+++ b/web/pgadmin/__init__.py
@@ -952,6 +952,9 @@ def inject_blueprint():
         return {
             'current_app': current_app,
             'current_blueprint': current_blueprint,
+            # Per-request Content-Security-Policy nonce, for use on inline
+            # <script>/<style> tags when a nonce based CSP is configured.
+            'csp_nonce': SecurityHeaders.get_nonce(),
         }
 
     @app.errorhandler(Exception)
diff --git a/web/pgadmin/templates/base.html b/web/pgadmin/templates/base.html
index 5c96784a6ab..9dcb9f62ea3 100644
--- a/web/pgadmin/templates/base.html
+++ b/web/pgadmin/templates/base.html
@@ -10,7 +10,7 @@
 
     <!-- To set pgAdmin4 shortcut icon in browser -->
     <link rel="shortcut icon" href="{{ url_for('redirects.favicon') }}"/>
-    <style>
+    <style nonce="{{ csp_nonce }}">
         .pg-sp-container {
             position: absolute;
             min-width: 100%;
@@ -43,14 +43,18 @@
      <!--View specified stylesheets-->
     {% block css_link %}{% endblock %}
 
-    <script type="application/javascript">
+    <!-- Per-request CSP nonce for webpack's dynamically injected assets -->
+    <script type="application/javascript" nonce="{{ csp_nonce }}">
+        window.__webpack_nonce__ = "{{ csp_nonce }}";
+    </script>
+    <script type="application/javascript" nonce="{{ csp_nonce }}">
         /* This is used to change publicPath of webpack at runtime */
         window.resourceBasePath = "{{ url_for('static', filename='js') }}/generated/";
     </script>
-    <script type="application/javascript"
+    <script type="application/javascript" nonce="{{ csp_nonce }}"
         src="{{ url_for('static', filename='vendor/require/require.js' if config.DEBUG else 'vendor/require/require.min.js') }}"></script>
     <!-- Base template scripts -->
-    <script type="application/javascript">
+    <script type="application/javascript" nonce="{{ csp_nonce }}">
             require.config({
                 baseUrl: '',
 {% if config.APP_VERSION_PARAM is not none and config.APP_VERSION_PARAM != '' %}
@@ -73,15 +77,15 @@
             });
 
     </script>
-    <script type="application/javascript" src="{{ url_for('static', filename='js/generated/vendor.react.js') }}" ></script>
-    <script type="application/javascript" src="{{ url_for('static', filename='js/generated/vendor.main.js') }}" ></script>
-    <script type="application/javascript" src="{{ url_for('static', filename='js/generated/vendor.others.js') }}" ></script>
-    <script type="application/javascript" src="{{ url_for('static', filename='js/generated/vendor.sqleditor.js') }}"></script>
-    <script type="application/javascript" src="{{ url_for('static', filename='js/generated/pgadmin_commons.js') }}" ></script>
+    <script type="application/javascript" nonce="{{ csp_nonce }}" src="{{ url_for('static', filename='js/generated/vendor.react.js') }}" ></script>
+    <script type="application/javascript" nonce="{{ csp_nonce }}" src="{{ url_for('static', filename='js/generated/vendor.main.js') }}" ></script>
+    <script type="application/javascript" nonce="{{ csp_nonce }}" src="{{ url_for('static', filename='js/generated/vendor.others.js') }}" ></script>
+    <script type="application/javascript" nonce="{{ csp_nonce }}" src="{{ url_for('static', filename='js/generated/vendor.sqleditor.js') }}"></script>
+    <script type="application/javascript" nonce="{{ csp_nonce }}" src="{{ url_for('static', filename='js/generated/pgadmin_commons.js') }}" ></script>
 
 </head>
 <body>
-<style>
+<style nonce="{{ csp_nonce }}">
 body {
   -webkit-user-select: none;
   -moz-user-select: none;
@@ -100,7 +104,7 @@
 <![endif]-->
 
 {% block body %}{% endblock %}
-<script type="application/javascript">
+<script type="application/javascript" nonce="{{ csp_nonce }}">
             {% block init_script %}{% endblock %}
 </script>
 
diff --git a/web/pgadmin/templates/security/render_page.html b/web/pgadmin/templates/security/render_page.html
index 43d6cc38e07..bc15bf5334b 100644
--- a/web/pgadmin/templates/security/render_page.html
+++ b/web/pgadmin/templates/security/render_page.html
@@ -4,7 +4,7 @@
     'messages': get_flashed_messages(with_categories=true)
 } %}
 {% block body %}
-<style>
+<style nonce="{{ csp_nonce }}">
     #root:not(:empty) + .pg-sp-container {
         display: none;
     }
diff --git a/web/pgadmin/tools/debugger/templates/debugger/direct.html b/web/pgadmin/tools/debugger/templates/debugger/direct.html
index 85568b31475..8efef467206 100644
--- a/web/pgadmin/tools/debugger/templates/debugger/direct.html
+++ b/web/pgadmin/tools/debugger/templates/debugger/direct.html
@@ -17,7 +17,7 @@
 }
 {% endblock %}
 {% block body %}
-<style>
+<style nonce="{{ csp_nonce }}">
     #debugger-main-container {
         display: flex;
         flex-direction: column;
@@ -29,7 +29,7 @@
     }
 </style>
 {% if is_desktop_mode and is_linux %}
-<style>
+<style nonce="{{ csp_nonce }}">
     body
 </style>
 {% endif %}
diff --git a/web/pgadmin/tools/erd/templates/erd/index.html b/web/pgadmin/tools/erd/templates/erd/index.html
index 363986e4100..8597651aa00 100644
--- a/web/pgadmin/tools/erd/templates/erd/index.html
+++ b/web/pgadmin/tools/erd/templates/erd/index.html
@@ -5,7 +5,7 @@
 <link type="text/css" rel="stylesheet" href="{{ url_for('browser.browser_css')}}"/>
 {% endblock %}
 {% block body %}
-<style>
+<style nonce="{{ csp_nonce }}">
     body {padding: 0px;}
     #erd-tool-container {
         display: flex;
diff --git a/web/pgadmin/tools/psql/templates/psql/index.html b/web/pgadmin/tools/psql/templates/psql/index.html
index 3d59be987aa..df4cdb63709 100644
--- a/web/pgadmin/tools/psql/templates/psql/index.html
+++ b/web/pgadmin/tools/psql/templates/psql/index.html
@@ -2,7 +2,7 @@
 {% block title %}{{title}}{% endblock %}
 
 {% block css_link %}
-<style>
+<style nonce="{{ csp_nonce }}">
     #psql-container {
         display: flex;
         flex-direction: column;
diff --git a/web/pgadmin/tools/schema_diff/templates/schema_diff/index.html b/web/pgadmin/tools/schema_diff/templates/schema_diff/index.html
index ecf6b196d45..69c523126a5 100644
--- a/web/pgadmin/tools/schema_diff/templates/schema_diff/index.html
+++ b/web/pgadmin/tools/schema_diff/templates/schema_diff/index.html
@@ -15,7 +15,7 @@
 }
 {% endblock %}
 {% block css_link %}
-<style>
+<style nonce="{{ csp_nonce }}">
   #schema-diff-main-container {
         display: flex;
         flex-direction: column;
diff --git a/web/pgadmin/tools/sqleditor/templates/sqleditor/index.html b/web/pgadmin/tools/sqleditor/templates/sqleditor/index.html
index 28e5978a951..f575dff5250 100644
--- a/web/pgadmin/tools/sqleditor/templates/sqleditor/index.html
+++ b/web/pgadmin/tools/sqleditor/templates/sqleditor/index.html
@@ -5,7 +5,7 @@
 <link type="text/css" rel="stylesheet" href="{{ url_for('browser.browser_css')}}"/>
 {% endblock %}
 {% block body %}
-<style>
+<style nonce="{{ csp_nonce }}">
     body {padding: 0px;}
     #sqleditor-container {
         display: flex;
diff --git a/web/pgadmin/utils/security_headers.py b/web/pgadmin/utils/security_headers.py
index 2e56c0711e0..0c71f58be15 100644
--- a/web/pgadmin/utils/security_headers.py
+++ b/web/pgadmin/utils/security_headers.py
@@ -7,17 +7,52 @@
 #
 #########################################################################
 
+import secrets
+
+from flask import g
+
 import config
 
+# Token that may be placed in the CONTENT_SECURITY_POLICY config value. It is
+# substituted at runtime with a freshly generated, per-request nonce so that
+# admins can opt-in to a nonce based policy, e.g.:
+#   CONTENT_SECURITY_POLICY = "script-src 'self' 'nonce-{nonce}';"
+CSP_NONCE_PLACEHOLDER = '{nonce}'
+
 
 class SecurityHeaders:
 
+    @staticmethod
+    def get_nonce():
+        """
+        Return the Content-Security-Policy nonce for the current request.
+
+        The value is generated once and cached on flask.g so that the exact
+        same nonce is emitted both in the rendered template (on inline
+        <script>/<style> tags) and in the Content-Security-Policy response
+        header.
+        """
+        if not hasattr(g, 'csp_nonce'):
+            g.csp_nonce = secrets.token_urlsafe(16)
+        return g.csp_nonce
+
+    @staticmethod
+    def get_content_security_policy():
+        """
+        Return the configured Content-Security-Policy, replacing the
+        ``{nonce}`` placeholder (if present) with the per-request nonce.
+        """
+        csp = getattr(config, 'CONTENT_SECURITY_POLICY', None)
+        if csp and CSP_NONCE_PLACEHOLDER in csp:
+            csp = csp.replace(
+                CSP_NONCE_PLACEHOLDER, SecurityHeaders.get_nonce())
+        return csp
+
     @staticmethod
     def set_response_headers(response):
         """set response security headers"""
 
         params_dict = {
-            'CONTENT_SECURITY_POLICY': 'Content-Security-Policy',
             'X_CONTENT_TYPE_OPTIONS': 'X-Content-Type-Options',
             'X_XSS_PROTECTION': 'X-XSS-Protection',
             'WEB_SERVER': 'Server',
@@ -35,6 +70,11 @@ def set_response_headers(response):
             response.headers["Strict-Transport-Security"] = \
                 config.STRICT_TRANSPORT_SECURITY
 
+        # Content-Security-Policy (with optional per-request nonce support)
+        csp = SecurityHeaders.get_content_security_policy()
+        if csp:
+            response.headers['Content-Security-Policy'] = csp
+
         # add other security options
         for key in params_dict:
             if key in config.__dict__ and config.__dict__[key] != "" \