diff --git a/src/compiler/checker.ts b/src/compiler/checker.ts
index 51c9493b61721..73fb7af6a4609 100644
--- a/src/compiler/checker.ts
+++ b/src/compiler/checker.ts
@@ -13212,6 +13212,9 @@ export function createTypeChecker(host: TypeCheckerHost): TypeChecker {
     }
 
     function getBaseTypes(type: InterfaceType): BaseType[] {
+        if (!(getObjectFlags(type) & (ObjectFlags.ClassOrInterface | ObjectFlags.Reference))) {
+            return emptyArray;
+        }
         if (!type.baseTypesResolved) {
             if (pushTypeResolution(type, TypeSystemPropertyName.ResolvedBaseTypes)) {
                 if (type.objectFlags & ObjectFlags.Tuple) {
@@ -35053,28 +35056,14 @@ export function createTypeChecker(host: TypeCheckerHost): TypeChecker {
      * In that case we won't consider it used before its declaration, because it gets its value from the superclass' declaration.
      */
     function isPropertyDeclaredInAncestorClass(prop: Symbol): boolean {
-        if (!(prop.parent!.flags & SymbolFlags.Class)) {
-            return false;
-        }
-        let classType: InterfaceType | undefined = getTypeOfSymbol(prop.parent!) as InterfaceType;
-        while (true) {
-            classType = classType.symbol && getSuperClass(classType) as InterfaceType | undefined;
-            if (!classType) {
-                return false;
-            }
-            const superProperty = getPropertyOfType(classType, prop.escapedName);
-            if (superProperty && superProperty.valueDeclaration) {
-                return true;
+        if (prop.parent && prop.parent.flags & SymbolFlags.Class) {
+            const baseTypes = getBaseTypes(getDeclaredTypeOfSymbol(prop.parent) as InterfaceType);
+            if (baseTypes.length) {
+                const superProperty = getPropertyOfType(baseTypes[0], prop.escapedName);
+                return !!(superProperty && superProperty.valueDeclaration);
             }
         }
-    }
-
-    function getSuperClass(classType: InterfaceType): Type | undefined {
-        const x = getBaseTypes(classType);
-        if (x.length === 0) {
-            return undefined;
-        }
-        return getIntersectionType(x);
+        return false;
     }
 
     function reportNonexistentProperty(propNode: Identifier | PrivateIdentifier, containingType: Type, isUncheckedJS: boolean) {
diff --git a/tests/baselines/reference/checkInheritedProperty.errors.txt b/tests/baselines/reference/checkInheritedProperty.errors.txt
new file mode 100644
index 0000000000000..86c262303dd4d
--- /dev/null
+++ b/tests/baselines/reference/checkInheritedProperty.errors.txt
@@ -0,0 +1,17 @@
+checkInheritedProperty.ts(7,14): error TS2729: Property 'b' is used before its initialization.
+
+
+==== checkInheritedProperty.ts (1 errors) ====
+    class Base {
+    }
+    
+    declare const BaseFactory: new() => Base & { c: string }
+    
+    class Derived extends BaseFactory {
+        a = this.b
+                 ~
+!!! error TS2729: Property 'b' is used before its initialization.
+!!! related TS2728 checkInheritedProperty.ts:8:5: 'b' is declared here.
+        b = "abc"
+    }
+    
\ No newline at end of file
diff --git a/tests/baselines/reference/checkInheritedProperty.symbols b/tests/baselines/reference/checkInheritedProperty.symbols
new file mode 100644
index 0000000000000..c977d078ae24b
--- /dev/null
+++ b/tests/baselines/reference/checkInheritedProperty.symbols
@@ -0,0 +1,26 @@
+//// [tests/cases/compiler/checkInheritedProperty.ts] ////
+
+=== checkInheritedProperty.ts ===
+class Base {
+>Base : Symbol(Base, Decl(checkInheritedProperty.ts, 0, 0))
+}
+
+declare const BaseFactory: new() => Base & { c: string }
+>BaseFactory : Symbol(BaseFactory, Decl(checkInheritedProperty.ts, 3, 13))
+>Base : Symbol(Base, Decl(checkInheritedProperty.ts, 0, 0))
+>c : Symbol(c, Decl(checkInheritedProperty.ts, 3, 44))
+
+class Derived extends BaseFactory {
+>Derived : Symbol(Derived, Decl(checkInheritedProperty.ts, 3, 56))
+>BaseFactory : Symbol(BaseFactory, Decl(checkInheritedProperty.ts, 3, 13))
+
+    a = this.b
+>a : Symbol(Derived.a, Decl(checkInheritedProperty.ts, 5, 35))
+>this.b : Symbol(Derived.b, Decl(checkInheritedProperty.ts, 6, 14))
+>this : Symbol(Derived, Decl(checkInheritedProperty.ts, 3, 56))
+>b : Symbol(Derived.b, Decl(checkInheritedProperty.ts, 6, 14))
+
+    b = "abc"
+>b : Symbol(Derived.b, Decl(checkInheritedProperty.ts, 6, 14))
+}
+
diff --git a/tests/baselines/reference/checkInheritedProperty.types b/tests/baselines/reference/checkInheritedProperty.types
new file mode 100644
index 0000000000000..5abc92638b5a5
--- /dev/null
+++ b/tests/baselines/reference/checkInheritedProperty.types
@@ -0,0 +1,37 @@
+//// [tests/cases/compiler/checkInheritedProperty.ts] ////
+
+=== checkInheritedProperty.ts ===
+class Base {
+>Base : Base
+>     : ^^^^
+}
+
+declare const BaseFactory: new() => Base & { c: string }
+>BaseFactory : new () => Base & { c: string; }
+>            : ^^^^^^^^^^                     
+>c : string
+>  : ^^^^^^
+
+class Derived extends BaseFactory {
+>Derived : Derived
+>        : ^^^^^^^
+>BaseFactory : Base & { c: string; }
+>            : ^^^^^^^^^^^^      ^^^
+
+    a = this.b
+>a : string
+>  : ^^^^^^
+>this.b : string
+>       : ^^^^^^
+>this : this
+>     : ^^^^
+>b : string
+>  : ^^^^^^
+
+    b = "abc"
+>b : string
+>  : ^^^^^^
+>"abc" : "abc"
+>      : ^^^^^
+}
+
diff --git a/tests/baselines/reference/noCrashOnMixin2.errors.txt b/tests/baselines/reference/noCrashOnMixin2.errors.txt
new file mode 100644
index 0000000000000..d7e28ae49b003
--- /dev/null
+++ b/tests/baselines/reference/noCrashOnMixin2.errors.txt
@@ -0,0 +1,41 @@
+noCrashOnMixin2.ts(11,33): error TS2370: A rest parameter must be of an array type.
+noCrashOnMixin2.ts(11,40): error TS1047: A rest parameter cannot be optional.
+noCrashOnMixin2.ts(14,12): error TS2545: A mixin class must have a constructor with a single rest parameter of type 'any[]'.
+noCrashOnMixin2.ts(23,9): error TS2674: Constructor of class 'Abstract' is protected and only accessible within the class declaration.
+
+
+==== noCrashOnMixin2.ts (4 errors) ====
+    // https://github.com/microsoft/TypeScript/issues/62921
+    
+    class Abstract {
+        protected constructor() {
+        }
+    }
+    
+    class Concrete extends Abstract {
+    }
+    
+    type Constructor<T = {}> = new (...args?: any[]) => T;
+                                    ~~~~~~~~~~~~~~~
+!!! error TS2370: A rest parameter must be of an array type.
+                                           ~
+!!! error TS1047: A rest parameter cannot be optional.
+    
+    function Mixin<TBase extends Constructor>(Base: TBase) {
+        return class extends Base {
+               ~~~~~
+!!! error TS2545: A mixin class must have a constructor with a single rest parameter of type 'any[]'.
+        };
+    }
+    
+    class Empty {
+    }
+    
+    class CrashTrigger extends Mixin(Empty) {
+        public trigger() {
+            new Concrete();
+            ~~~~~~~~~~~~~~
+!!! error TS2674: Constructor of class 'Abstract' is protected and only accessible within the class declaration.
+        }
+    }
+    
\ No newline at end of file
diff --git a/tests/baselines/reference/noCrashOnMixin2.symbols b/tests/baselines/reference/noCrashOnMixin2.symbols
new file mode 100644
index 0000000000000..428e2e5de280f
--- /dev/null
+++ b/tests/baselines/reference/noCrashOnMixin2.symbols
@@ -0,0 +1,53 @@
+//// [tests/cases/compiler/noCrashOnMixin2.ts] ////
+
+=== noCrashOnMixin2.ts ===
+// https://github.com/microsoft/TypeScript/issues/62921
+
+class Abstract {
+>Abstract : Symbol(Abstract, Decl(noCrashOnMixin2.ts, 0, 0))
+
+    protected constructor() {
+    }
+}
+
+class Concrete extends Abstract {
+>Concrete : Symbol(Concrete, Decl(noCrashOnMixin2.ts, 5, 1))
+>Abstract : Symbol(Abstract, Decl(noCrashOnMixin2.ts, 0, 0))
+}
+
+type Constructor<T = {}> = new (...args?: any[]) => T;
+>Constructor : Symbol(Constructor, Decl(noCrashOnMixin2.ts, 8, 1))
+>T : Symbol(T, Decl(noCrashOnMixin2.ts, 10, 17))
+>args : Symbol(args, Decl(noCrashOnMixin2.ts, 10, 32))
+>T : Symbol(T, Decl(noCrashOnMixin2.ts, 10, 17))
+
+function Mixin<TBase extends Constructor>(Base: TBase) {
+>Mixin : Symbol(Mixin, Decl(noCrashOnMixin2.ts, 10, 54))
+>TBase : Symbol(TBase, Decl(noCrashOnMixin2.ts, 12, 15))
+>Constructor : Symbol(Constructor, Decl(noCrashOnMixin2.ts, 8, 1))
+>Base : Symbol(Base, Decl(noCrashOnMixin2.ts, 12, 42))
+>TBase : Symbol(TBase, Decl(noCrashOnMixin2.ts, 12, 15))
+
+    return class extends Base {
+>Base : Symbol(Base, Decl(noCrashOnMixin2.ts, 12, 42))
+
+    };
+}
+
+class Empty {
+>Empty : Symbol(Empty, Decl(noCrashOnMixin2.ts, 15, 1))
+}
+
+class CrashTrigger extends Mixin(Empty) {
+>CrashTrigger : Symbol(CrashTrigger, Decl(noCrashOnMixin2.ts, 18, 1))
+>Mixin : Symbol(Mixin, Decl(noCrashOnMixin2.ts, 10, 54))
+>Empty : Symbol(Empty, Decl(noCrashOnMixin2.ts, 15, 1))
+
+    public trigger() {
+>trigger : Symbol(CrashTrigger.trigger, Decl(noCrashOnMixin2.ts, 20, 41))
+
+        new Concrete();
+>Concrete : Symbol(Concrete, Decl(noCrashOnMixin2.ts, 5, 1))
+    }
+}
+
diff --git a/tests/baselines/reference/noCrashOnMixin2.types b/tests/baselines/reference/noCrashOnMixin2.types
new file mode 100644
index 0000000000000..e568789976804
--- /dev/null
+++ b/tests/baselines/reference/noCrashOnMixin2.types
@@ -0,0 +1,68 @@
+//// [tests/cases/compiler/noCrashOnMixin2.ts] ////
+
+=== noCrashOnMixin2.ts ===
+// https://github.com/microsoft/TypeScript/issues/62921
+
+class Abstract {
+>Abstract : Abstract
+>         : ^^^^^^^^
+
+    protected constructor() {
+    }
+}
+
+class Concrete extends Abstract {
+>Concrete : Concrete
+>         : ^^^^^^^^
+>Abstract : Abstract
+>         : ^^^^^^^^
+}
+
+type Constructor<T = {}> = new (...args?: any[]) => T;
+>Constructor : Constructor<T>
+>            : ^^^^^^^^^^^^^^
+>args : any[] | undefined
+>     : ^^^^^^^^^^^^^^^^^
+
+function Mixin<TBase extends Constructor>(Base: TBase) {
+>Mixin : <TBase extends Constructor>(Base: TBase) => { new (...args?: any[]): (Anonymous class); prototype: Mixin<any>.(Anonymous class); } & TBase
+>      : ^     ^^^^^^^^^           ^^    ^^     ^^^^^^^^^^^^^^^    ^^^     ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
+>Base : TBase
+>     : ^^^^^
+
+    return class extends Base {
+>class extends Base {    } : { new (...args?: any[]): (Anonymous class); prototype: Mixin<any>.(Anonymous class); } & TBase
+>                          : ^^^^^^^^^^    ^^^     ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
+>Base : {}
+>     : ^^
+
+    };
+}
+
+class Empty {
+>Empty : Empty
+>      : ^^^^^
+}
+
+class CrashTrigger extends Mixin(Empty) {
+>CrashTrigger : CrashTrigger
+>             : ^^^^^^^^^^^^
+>Mixin(Empty) : Mixin<typeof Empty>.(Anonymous class)
+>             : ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
+>Mixin : <TBase extends Constructor>(Base: TBase) => { new (...args?: any[]): (Anonymous class); prototype: Mixin<any>.(Anonymous class); } & TBase
+>      : ^     ^^^^^^^^^           ^^    ^^     ^^^^^^^^^^^^^^^    ^^^     ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
+>Empty : typeof Empty
+>      : ^^^^^^^^^^^^
+
+    public trigger() {
+>trigger : () => void
+>        : ^^^^^^^^^^
+
+        new Concrete();
+>new Concrete() : any
+>               : ^^^
+>Concrete : typeof Concrete
+>         : ^^^^^^^^^^^^^^^
+    }
+}
+
diff --git a/tests/cases/compiler/checkInheritedProperty.ts b/tests/cases/compiler/checkInheritedProperty.ts
new file mode 100644
index 0000000000000..12960b990c5cc
--- /dev/null
+++ b/tests/cases/compiler/checkInheritedProperty.ts
@@ -0,0 +1,12 @@
+// @strict: true
+// @noEmit: true
+
+class Base {
+}
+
+declare const BaseFactory: new() => Base & { c: string }
+
+class Derived extends BaseFactory {
+    a = this.b
+    b = "abc"
+}
diff --git a/tests/cases/compiler/noCrashOnMixin2.ts b/tests/cases/compiler/noCrashOnMixin2.ts
new file mode 100644
index 0000000000000..f6ddccf9480d2
--- /dev/null
+++ b/tests/cases/compiler/noCrashOnMixin2.ts
@@ -0,0 +1,28 @@
+// @strict: true
+// @noEmit: true
+
+// https://github.com/microsoft/TypeScript/issues/62921
+
+class Abstract {
+    protected constructor() {
+    }
+}
+
+class Concrete extends Abstract {
+}
+
+type Constructor<T = {}> = new (...args?: any[]) => T;
+
+function Mixin<TBase extends Constructor>(Base: TBase) {
+    return class extends Base {
+    };
+}
+
+class Empty {
+}
+
+class CrashTrigger extends Mixin(Empty) {
+    public trigger() {
+        new Concrete();
+    }
+}