diff --git a/src/Symfony/Tests/Fixtures/DummyValidatedEntityWithGroupSequence.php b/src/Symfony/Tests/Fixtures/DummyValidatedEntityWithGroupSequence.php
index 354207b6eb4..3e6c9f75bfa 100644
--- a/src/Symfony/Tests/Fixtures/DummyValidatedEntityWithGroupSequence.php
+++ b/src/Symfony/Tests/Fixtures/DummyValidatedEntityWithGroupSequence.php
@@ -20,7 +20,7 @@
  *
  * @author Baptiste Meyer <baptiste.meyer@gmail.com>
  */
-#[Assert\GroupSequence(['dummy', 'DummyValidatedEntityWithGroupSequence'])]
+#[Assert\GroupSequence(['dummy', 'DummyValidatedEntityWithGroupSequence', ['dummy2'], new Assert\GroupSequence(['dummy3'])])]
 class DummyValidatedEntityWithGroupSequence
 {
     /**
@@ -73,6 +73,18 @@ class DummyValidatedEntityWithGroupSequence
     #[Assert\NotNull(groups: ['dummy'])]
     public $dummyGroup;
 
+    /**
+     * @var string A dummy group
+     */
+    #[Assert\NotNull(groups: ['dummy2'])]
+    public $dummyGroup2;
+
+    /**
+     * @var string A dummy group
+     */
+    #[Assert\NotNull(groups: ['dummy3'])]
+    public $dummyGroup3;
+
     /**
      * @var string A dummy url
      */
diff --git a/src/Symfony/Tests/Validator/Metadata/Property/ValidatorPropertyMetadataFactoryTest.php b/src/Symfony/Tests/Validator/Metadata/Property/ValidatorPropertyMetadataFactoryTest.php
index 7b2b6031ac3..29b04694979 100644
--- a/src/Symfony/Tests/Validator/Metadata/Property/ValidatorPropertyMetadataFactoryTest.php
+++ b/src/Symfony/Tests/Validator/Metadata/Property/ValidatorPropertyMetadataFactoryTest.php
@@ -142,13 +142,14 @@ public function testCreateWithPropertyWithoutConstraints(): void
         $this->assertEquals($expectedPropertyMetadata, $resultedPropertyMetadata);
     }
 
-    public function testCreateWithPropertyWithRequiredConstraintsAndGroupSequence(): void
+    #[DataProvider('createWithPropertyWithRequiredConstraintsAndGroupSequenceDataProvider')]
+    public function testCreateWithPropertyWithRequiredConstraintsAndGroupSequence(string $propertyName): void
     {
         $propertyMetadata = (new ApiProperty())->withDescription('A dummy group')->withReadable(true)->withWritable(true);
         $expectedPropertyMetadata = $propertyMetadata->withRequired(true);
 
         $decoratedPropertyMetadataFactory = $this->prophesize(PropertyMetadataFactoryInterface::class);
-        $decoratedPropertyMetadataFactory->create(DummyValidatedEntityWithGroupSequence::class, 'dummyGroup', [])->willReturn($propertyMetadata)->shouldBeCalled();
+        $decoratedPropertyMetadataFactory->create(DummyValidatedEntityWithGroupSequence::class, $propertyName, [])->willReturn($propertyMetadata)->shouldBeCalled();
 
         $validatorClassMetadata = new ClassMetadata(DummyValidatedEntityWithGroupSequence::class);
         (new AttributeLoader())->loadClassMetadata($validatorClassMetadata);
@@ -161,11 +162,21 @@ public function testCreateWithPropertyWithRequiredConstraintsAndGroupSequence():
             $decoratedPropertyMetadataFactory->reveal(),
             []
         );
-        $resultedPropertyMetadata = $validatorPropertyMetadataFactory->create(DummyValidatedEntityWithGroupSequence::class, 'dummyGroup');
+        $resultedPropertyMetadata = $validatorPropertyMetadataFactory->create(DummyValidatedEntityWithGroupSequence::class, $propertyName);
 
         $this->assertEquals($expectedPropertyMetadata, $resultedPropertyMetadata);
     }
 
+    /**
+     * @return iterable<array{string}>
+     */
+    public static function createWithPropertyWithRequiredConstraintsAndGroupSequenceDataProvider(): iterable
+    {
+        yield ['dummyGroup'];
+        yield ['dummyGroup2'];
+        yield ['dummyGroup3'];
+    }
+
     public function testCreateWithPropertyWithRightValidationGroupsAndRequiredConstraints(): void
     {
         $propertyMetadata = (new ApiProperty())->withDescription('A dummy group')->withReadable(true)->withWritable(true);
diff --git a/src/Symfony/Validator/Metadata/Property/ValidatorPropertyMetadataFactory.php b/src/Symfony/Validator/Metadata/Property/ValidatorPropertyMetadataFactory.php
index ddfa7991f39..3fdc024188e 100644
--- a/src/Symfony/Validator/Metadata/Property/ValidatorPropertyMetadataFactory.php
+++ b/src/Symfony/Validator/Metadata/Property/ValidatorPropertyMetadataFactory.php
@@ -149,12 +149,14 @@ public function create(string $resourceClass, string $property, array $options =
 
     /**
      * Returns the list of validation groups.
+     *
+     * @return array<string>
      */
     private function getValidationGroups(ValidatorClassMetadataInterface $classMetadata, array $options): array
     {
         if (isset($options['validation_groups'])) {
             if ($options['validation_groups'] instanceof GroupSequence) {
-                return $options['validation_groups']->groups;
+                return $this->getGroupSequenceValidationGroups($options['validation_groups']);
             }
 
             if (!\is_callable($options['validation_groups'])) {
@@ -163,7 +165,7 @@ private function getValidationGroups(ValidatorClassMetadataInterface $classMetad
         }
 
         if ($classMetadata->hasGroupSequence()) {
-            return $classMetadata->getGroupSequence()->groups;
+            return $this->getGroupSequenceValidationGroups($classMetadata->getGroupSequence());
         }
 
         if (!method_exists($classMetadata, 'getDefaultGroup')) {
@@ -173,6 +175,25 @@ private function getValidationGroups(ValidatorClassMetadataInterface $classMetad
         return [$classMetadata->getDefaultGroup()];
     }
 
+    /**
+     * @return array<string>
+     */
+    private function getGroupSequenceValidationGroups(GroupSequence $groupSequence): array
+    {
+        $groups = [];
+        foreach ($groupSequence->groups as $subGroup) {
+            if (\is_array($subGroup)) {
+                $groups[] = $subGroup;
+            } elseif ($subGroup instanceof GroupSequence) {
+                $groups[] = $this->getGroupSequenceValidationGroups($subGroup);
+            } else {
+                $groups[] = [$subGroup];
+            }
+        }
+
+        return array_merge([], ...$groups);
+    }
+
     /**
      * Tests if the property is required because of its validation groups.
      */