diff --git a/core/camel-base-engine/src/main/java/org/apache/camel/impl/engine/DefaultSupervisingRouteController.java b/core/camel-base-engine/src/main/java/org/apache/camel/impl/engine/DefaultSupervisingRouteController.java
index 0e21c2a190791..a04b5200540cb 100644
--- a/core/camel-base-engine/src/main/java/org/apache/camel/impl/engine/DefaultSupervisingRouteController.java
+++ b/core/camel-base-engine/src/main/java/org/apache/camel/impl/engine/DefaultSupervisingRouteController.java
@@ -688,7 +688,20 @@ void start(RouteHolder route) {
                             try {
                                 logger.info("Restarting route: {} attempt: {}", r.getId(), attempt);
                                 EventHelper.notifyRouteRestarting(getCamelContext(), r.get(), attempt);
-                                doStartRoute(r, false, rx -> DefaultSupervisingRouteController.super.startRoute(rx.getId()));
+                                lock.lock();
+                                try {
+                                    // the route may have been stopped or started manually (which cancels this task),
+                                    // or Camel may be stopping, while this attempt waited for the lock
+                                    if (routes.get(r) != context || context.getStatus() != BackOffTimer.Task.Status.Active
+                                            || !getCamelContext().isRunAllowed()) {
+                                        logger.info("Restarting route: {} attempt: {} is cancelled", r.getId(), attempt);
+                                        return false;
+                                    }
+                                    doStartRoute(r, false,
+                                            rx -> DefaultSupervisingRouteController.super.startRoute(rx.getId()));
+                                } finally {
+                                    lock.unlock();
+                                }
                                 logger.info("Route: {} started after {} attempts", r.getId(), attempt);
                                 return false;
                             } catch (Exception e) {
diff --git a/core/camel-core/src/test/java/org/apache/camel/impl/engine/DefaultSupervisingRouteControllerStopWhileRestartingTest.java b/core/camel-core/src/test/java/org/apache/camel/impl/engine/DefaultSupervisingRouteControllerStopWhileRestartingTest.java
new file mode 100644
index 0000000000000..d04d6c2d865e1
--- /dev/null
+++ b/core/camel-core/src/test/java/org/apache/camel/impl/engine/DefaultSupervisingRouteControllerStopWhileRestartingTest.java
@@ -0,0 +1,128 @@
+/*
+ * Licensed to the Apache Software Foundation (ASF) under one or more
+ * contributor license agreements.  See the NOTICE file distributed with
+ * this work for additional information regarding copyright ownership.
+ * The ASF licenses this file to You under the Apache License, Version 2.0
+ * (the "License"); you may not use this file except in compliance with
+ * the License.  You may obtain a copy of the License at
+ *
+ *      http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+package org.apache.camel.impl.engine;
+
+import java.util.Map;
+import java.util.concurrent.CountDownLatch;
+import java.util.concurrent.TimeUnit;
+import java.util.concurrent.atomic.AtomicBoolean;
+import java.util.concurrent.atomic.AtomicReference;
+
+import org.apache.camel.Consumer;
+import org.apache.camel.ContextTestSupport;
+import org.apache.camel.Endpoint;
+import org.apache.camel.Processor;
+import org.apache.camel.Producer;
+import org.apache.camel.builder.RouteBuilder;
+import org.apache.camel.spi.CamelEvent;
+import org.apache.camel.spi.CamelEvent.RouteRestartingEvent;
+import org.apache.camel.spi.SupervisingRouteController;
+import org.apache.camel.support.DefaultComponent;
+import org.apache.camel.support.DefaultConsumer;
+import org.apache.camel.support.DefaultEndpoint;
+import org.apache.camel.support.SimpleEventNotifierSupport;
+import org.apache.camel.util.backoff.BackOffTimer;
+import org.junit.jupiter.api.Test;
+
+import static org.awaitility.Awaitility.await;
+import static org.junit.jupiter.api.Assertions.assertEquals;
+import static org.junit.jupiter.api.Assertions.assertTrue;
+
+/**
+ * A route that is stopped manually while its restart attempt is running must not be started by that attempt.
+ */
+class DefaultSupervisingRouteControllerStopWhileRestartingTest extends ContextTestSupport {
+
+    private final AtomicBoolean failing = new AtomicBoolean(true);
+
+    @Override
+    public boolean isUseRouteBuilder() {
+        return false;
+    }
+
+    @Test
+    void testStopRouteWhileRestartAttemptIsRunning() throws Exception {
+        CountDownLatch attemptStarted = new CountDownLatch(1);
+        CountDownLatch routeStopped = new CountDownLatch(1);
+        AtomicReference<BackOffTimer.Task> restartTask = new AtomicReference<>();
+
+        context.addComponent("flaky", new FlakyComponent());
+        context.addRoutes(new RouteBuilder() {
+            @Override
+            public void configure() {
+                from("flaky:start").routeId("flaky").to("mock:result");
+            }
+        });
+
+        SupervisingRouteController src = context.getRouteController().supervising();
+        src.setBackOffDelay(10);
+        src.setBackOffMaxAttempts(3);
+        src.setInitialDelay(10);
+
+        context.getManagementStrategy().addEventNotifier(new SimpleEventNotifierSupport() {
+            @Override
+            public void notify(CamelEvent event) throws Exception {
+                if (event instanceof RouteRestartingEvent rre && "flaky".equals(rre.getRoute().getRouteId())
+                        && restartTask.compareAndSet(null, src.getRestartingRouteState("flaky"))) {
+                    // the restart attempt is about to start the route: let the route be stopped first
+                    attemptStarted.countDown();
+                    assertTrue(routeStopped.await(10, TimeUnit.SECONDS));
+                }
+            }
+        });
+
+        context.start();
+        assertTrue(attemptStarted.await(10, TimeUnit.SECONDS));
+
+        // the cause is fixed, but the route is stopped manually while the restart attempt is running
+        failing.set(false);
+        context.getRouteController().stopRoute("flaky");
+        assertEquals("Stopped", context.getRouteController().getRouteStatus("flaky").toString());
+        routeStopped.countDown();
+
+        // the restart attempt finishes, and the route stays stopped
+        await().atMost(10, TimeUnit.SECONDS)
+                .until(() -> restartTask.get().getStatus() == BackOffTimer.Task.Status.Completed);
+        assertEquals("Stopped", context.getRouteController().getRouteStatus("flaky").toString());
+    }
+
+    private final class FlakyComponent extends DefaultComponent {
+
+        @Override
+        protected Endpoint createEndpoint(String uri, String remaining, Map<String, Object> parameters) {
+            return new DefaultEndpoint(uri, this) {
+                @Override
+                public Producer createProducer() {
+                    throw new UnsupportedOperationException();
+                }
+
+                @Override
+                public Consumer createConsumer(Processor processor) {
+                    return new DefaultConsumer(this, processor) {
+                        @Override
+                        protected void doStart() throws Exception {
+                            if (failing.get()) {
+                                throw new IllegalStateException("Cannot connect");
+                            }
+                            super.doStart();
+                        }
+                    };
+                }
+            };
+        }
+    }
+}