diff --git a/src/wp-includes/class-wp-plugin-dependencies.php b/src/wp-includes/class-wp-plugin-dependencies.php
index c96b98d08b550..fab7406622a11 100644
--- a/src/wp-includes/class-wp-plugin-dependencies.php
+++ b/src/wp-includes/class-wp-plugin-dependencies.php
@@ -477,7 +477,7 @@ public static function check_plugin_dependencies_during_ajax() {
 			);
 		}
 
-		if ( is_multisite() && current_user_can( 'manage_network_plugins' ) ) {
+		if ( isset( $status['activateUrl'] ) && is_multisite() && current_user_can( 'manage_network_plugins' ) ) {
 			$status['activateUrl'] = add_query_arg( array( 'networkwide' => 1 ), $status['activateUrl'] );
 		}
 
diff --git a/tests/phpunit/tests/ajax/wpAjaxCheckPluginDependencies.php b/tests/phpunit/tests/ajax/wpAjaxCheckPluginDependencies.php
index 70dda155a4d79..9e27c0987d95b 100644
--- a/tests/phpunit/tests/ajax/wpAjaxCheckPluginDependencies.php
+++ b/tests/phpunit/tests/ajax/wpAjaxCheckPluginDependencies.php
@@ -273,8 +273,7 @@ public function test_should_not_return_activate_url_for_user_without_capability(
 	 * Tests that no activation URL is returned for a plugin that is already active.
 	 *
 	 * @ticket 65819
-	 *
-	 * @group ms-excluded
+	 * @ticket 66346
 	 */
 	public function test_should_not_return_activate_url_for_active_plugin() {
 		wp_set_current_user( self::$admin_id );
@@ -290,6 +289,27 @@ public function test_should_not_return_activate_url_for_active_plugin() {
 		$this->assertArrayNotHasKey( 'activateUrl', $response['data'], 'No activation URL should be returned.' );
 	}
 
+	/**
+	 * Tests that no activation URL is returned for a plugin that is network-activated.
+	 *
+	 * @ticket 66346
+	 *
+	 * @group ms-required
+	 */
+	public function test_should_not_return_activate_url_for_network_active_plugin() {
+		wp_set_current_user( self::$admin_id );
+
+		$this->set_installed_plugins( array( 'dependent/dependent.php' => '' ) );
+		update_site_option( 'active_sitewide_plugins', array( 'dependent/dependent.php' => time() ) );
+
+		$_POST['slug'] = 'dependent';
+
+		$response = $this->make_request();
+
+		$this->assertTrue( $response['success'], 'The request should succeed.' );
+		$this->assertArrayNotHasKey( 'activateUrl', $response['data'], 'No activation URL should be returned.' );
+	}
+
 	/**
 	 * Tests that a plugin whose dependencies are all active returns success.
 	 *