diff --git a/embedding/commentfilter/config.go b/embedding/commentfilter/config.go
index 0b023d6..906f4c5 100644
--- a/embedding/commentfilter/config.go
+++ b/embedding/commentfilter/config.go
@@ -23,6 +23,8 @@ const (
 	cStyleBlockCommentEnd   = "*/"
 	cStyleDocCommentStart   = "/**"
 	javaTextBlockDelimiter  = "\"\"\""
+	pythonDoubleQuoteBlock  = "\"\"\""
+	pythonSingleQuoteBlock  = "'''"
 	goRawStringDelimiter    = "`"
 	goQuoteChars            = "\"'"
 	jsQuoteChars            = "\"'`"
@@ -62,9 +64,9 @@ var filtersByExtension = map[string]filterEntry{
 	".proto": filterConfig(MarkerCommentFilter{Syntax: cStyleSyntax}, regularModes),
 
 	// Python
-	".py":  filterConfig(MarkerCommentFilter{Syntax: hashLineSyntax}, noneMode),
-	".pyi": filterConfig(MarkerCommentFilter{Syntax: hashLineSyntax}, noneMode),
-	".pyw": filterConfig(MarkerCommentFilter{Syntax: hashLineSyntax}, noneMode),
+	".py":  filterConfig(MarkerCommentFilter{Syntax: pythonSyntax}, noneMode),
+	".pyi": filterConfig(MarkerCommentFilter{Syntax: pythonSyntax}, noneMode),
+	".pyw": filterConfig(MarkerCommentFilter{Syntax: pythonSyntax}, noneMode),
 
 	// YAML
 	".yml":  filterConfig(MarkerCommentFilter{Syntax: hashLineSyntax}, noneMode),
@@ -131,6 +133,15 @@ var hashLineSyntax = CommentMarker{
 	QuoteChars: "\"'",
 }
 
+var pythonSyntax = CommentMarker{
+	Inline: []string{"#"},
+	TextBlocks: []TextBlockMarker{
+		{Delimiter: pythonDoubleQuoteBlock, Escapes: true},
+		{Delimiter: pythonSingleQuoteBlock, Escapes: true},
+	},
+	QuoteChars: "\"'",
+}
+
 var xmlSyntax = CommentMarker{
 	Block: []BlockMarker{
 		{Start: "<!--", End: "-->"},
diff --git a/embedding/commentfilter/python_filter_test.go b/embedding/commentfilter/python_filter_test.go
index a945342..ad39fc9 100644
--- a/embedding/commentfilter/python_filter_test.go
+++ b/embedding/commentfilter/python_filter_test.go
@@ -39,4 +39,33 @@ var _ = Describe("Python", func() {
 
 		assertFiltered("module.py", RetainNone, lines, expected)
 	})
+
+	It("should strip comments without treating triple-quoted string content as comments", func() {
+		lines := []string{
+			"# module comment",
+			"def message():",
+			"    \"\"\"",
+			"    Keep this # docstring text.",
+			"    \"\"\"",
+			`    escaped = """a\"""" # inline comment`,
+			"    value = '''",
+			"    Keep this # multiline text.",
+			"    ''' # inline comment",
+			"    return value # real comment",
+		}
+
+		expected := []string{
+			"def message():",
+			"    \"\"\"",
+			"    Keep this # docstring text.",
+			"    \"\"\"",
+			`    escaped = """a\"""" `,
+			"    value = '''",
+			"    Keep this # multiline text.",
+			"    ''' ",
+			"    return value ",
+		}
+
+		assertFiltered("module.py", RetainNone, lines, expected)
+	})
 })