diff --git a/monai/losses/unified_focal_loss.py b/monai/losses/unified_focal_loss.py
index 745513fec0..2b6212fb94 100644
--- a/monai/losses/unified_focal_loss.py
+++ b/monai/losses/unified_focal_loss.py
@@ -162,6 +162,8 @@ def __init__(
         gamma: float = 0.5,
         delta: float = 0.7,
         reduction: LossReduction | str = LossReduction.MEAN,
+        use_softmax: bool = False,
+        use_sigmoid: bool = False,
     ):
         """
         Args:
@@ -170,8 +172,14 @@ def __init__(
             weight : weight for each loss function. Defaults to 0.5.
             gamma : value of the exponent gamma in the definition of the Focal loss. Defaults to 0.5.
             delta : weight of the background. Defaults to 0.7.
-
-
+            reduction: {``"none"``, ``"mean"``, ``"sum"``}
+                Specifies the reduction to apply to the output. Defaults to ``"mean"``.
+            use_softmax: if True, use softmax to transform the input logits into probabilities.
+                Defaults to False. Mutually exclusive with ``use_sigmoid``.
+            use_sigmoid: if True, use sigmoid to transform the input logits into probabilities.
+                Defaults to False. Mutually exclusive with ``use_softmax``.
+                When both ``use_softmax`` and ``use_sigmoid`` are False, the input is assumed
+                to already be probabilities.
 
         Example:
             >>> import torch
@@ -182,22 +190,25 @@ def __init__(
             >>> fl(pred, grnd)
         """
         super().__init__(reduction=LossReduction(reduction).value)
+        if use_softmax and use_sigmoid:
+            raise ValueError("use_softmax and use_sigmoid are mutually exclusive.")
         self.to_onehot_y = to_onehot_y
         self.num_classes = num_classes
         self.gamma = gamma
         self.delta = delta
         self.weight: float = weight
+        self.use_softmax = use_softmax
+        self.use_sigmoid = use_sigmoid
         self.asy_focal_loss = AsymmetricFocalLoss(gamma=self.gamma, delta=self.delta)
         self.asy_focal_tversky_loss = AsymmetricFocalTverskyLoss(gamma=self.gamma, delta=self.delta)
 
-    # TODO: Implement this  function to support multiple classes segmentation
     def forward(self, y_pred: torch.Tensor, y_true: torch.Tensor) -> torch.Tensor:
         """
         Args:
             y_pred : the shape should be BNH[WD], where N is the number of classes.
                 It only supports binary segmentation.
-                The input should be the original logits since it will be transformed by
-                    a sigmoid in the forward function.
+                The input can be raw logits or probabilities depending on ``use_softmax``
+                and ``use_sigmoid`` settings.
             y_true : the shape should be BNH[WD], where N is the number of classes.
                 It only supports binary segmentation.
 
@@ -213,6 +224,13 @@ def forward(self, y_pred: torch.Tensor, y_true: torch.Tensor) -> torch.Tensor:
         if len(y_pred.shape) != 4 and len(y_pred.shape) != 5:
             raise ValueError(f"input shape must be 4 or 5, but got {y_pred.shape}")
 
+        # Apply activation BEFORE one_hot encoding, since one_hot uses
+        # values as scatter indices and raw logits would cause index errors.
+        if self.use_softmax:
+            y_pred = torch.softmax(y_pred, dim=1)
+        elif self.use_sigmoid:
+            y_pred = torch.sigmoid(y_pred)
+
         if y_pred.shape[1] == 1:
             y_pred = one_hot(y_pred, num_classes=self.num_classes)
             y_true = one_hot(y_true, num_classes=self.num_classes)
diff --git a/tests/losses/test_unified_focal_loss.py b/tests/losses/test_unified_focal_loss.py
index 3b868a560e..3fa7354cf2 100644
--- a/tests/losses/test_unified_focal_loss.py
+++ b/tests/losses/test_unified_focal_loss.py
@@ -61,6 +61,24 @@ def test_with_cuda(self):
         print(output)
         np.testing.assert_allclose(output.detach().cpu().numpy(), 0.0, atol=1e-4, rtol=1e-4)
 
+    def test_use_sigmoid(self):
+        loss = AsymmetricUnifiedFocalLoss(use_sigmoid=True)
+        y_pred = torch.tensor([[[[10.0, -10], [-10, 10.0]]], [[[10.0, -10], [-10, 10.0]]]])
+        y_true = torch.tensor([[[[1.0, 0], [0, 1.0]]], [[[1.0, 0], [0, 1.0]]]])
+        result = loss(y_pred, y_true)
+        self.assertTrue(result.item() >= 0)
+
+    def test_use_softmax(self):
+        loss = AsymmetricUnifiedFocalLoss(use_softmax=True)
+        y_pred = torch.tensor([[[[10.0, -10], [-10, 10.0]]], [[[10.0, -10], [-10, 10.0]]]])
+        y_true = torch.tensor([[[[1.0, 0], [0, 1.0]]], [[[1.0, 0], [0, 1.0]]]])
+        result = loss(y_pred, y_true)
+        self.assertTrue(result.item() >= 0)
+
+    def test_mutually_exclusive(self):
+        with self.assertRaises(ValueError):
+            AsymmetricUnifiedFocalLoss(use_softmax=True, use_sigmoid=True)
+
 
 if __name__ == "__main__":
     unittest.main()