diff --git a/src/org/labkey/targetedms/view/precursorConflictResolutionView.jsp b/src/org/labkey/targetedms/view/precursorConflictResolutionView.jsp
index 90a66ebdc..caa2fcb10 100644
--- a/src/org/labkey/targetedms/view/precursorConflictResolutionView.jsp
+++ b/src/org/labkey/targetedms/view/precursorConflictResolutionView.jsp
@@ -119,12 +119,12 @@ $(document).ready(function () {
         {
             row.child.hide();
             tr.removeClass('shown');
-            $("." + cls).children('img').attr('src', "<%=getWebappURL("_images/plus.gif")%>");
+            $("." + cls).children('img').attr('src', "<%=getWebappURL("_images/plus.gif")%>").attr('alt', 'Expand row details');
         }
         else {
             row.child.show();
             tr.addClass('shown');
-            $("." + cls).children('img').attr('src', "<%=getWebappURL("_images/minus.gif")%>");
+            $("." + cls).children('img').attr('src', "<%=getWebappURL("_images/minus.gif")%>").attr('alt', 'Collapse row details');
         }
 
         if(!srcTd.hasClass('content_loaded'))
@@ -271,7 +271,7 @@ function toggleCheckboxSelection(element)
              <!--<td class="representative newPrecursor <%=precursor.getNewPrecursorId()%>"><%=precursor.getNewPrecursorId()%></td>-->
              <td class="representative details-control newPrecursor <%=precursor.getNewPrecursorId()%>">
                 <span class="<%=precursor.getNewPrecursorId()%>_<%=precursor.getOldPrecursorId()%>">
-                     <img src="<%=getWebappURL("_images/plus.gif")%>"/>
+                     <img src="<%=getWebappURL("_images/plus.gif")%>" alt="Expand row details"/>
                  </span>
              </td>
              <td class="representative newPrecursor <%=precursor.getNewPrecursorId()%>">
@@ -291,7 +291,7 @@ function toggleCheckboxSelection(element)
              <!--<td class="oldPrecursor <%=precursor.getNewPrecursorId()%>"><%=precursor.getOldPrecursorId()%></td>-->
              <td class="details-control oldPrecursor <%=precursor.getNewPrecursorId()%>">
                 <span class="<%=precursor.getNewPrecursorId()%>_<%=precursor.getOldPrecursorId()%>">
-                     <img src="<%=getWebappURL("_images/plus.gif")%>"/>
+                     <img src="<%=getWebappURL("_images/plus.gif")%>" alt="Expand row details"/>
                  </span>
              </td>
              <td class="oldPrecursor <%=precursor.getNewPrecursorId()%>">
diff --git a/webapp/TargetedMS/css/qcTrendPlotReport.css b/webapp/TargetedMS/css/qcTrendPlotReport.css
index b4434fed4..595b33192 100644
--- a/webapp/TargetedMS/css/qcTrendPlotReport.css
+++ b/webapp/TargetedMS/css/qcTrendPlotReport.css
@@ -70,6 +70,7 @@
     font-size: 18px;
     padding: 0 8px;
     border: solid #c0c0c0 1px;
+    background: none;
 }
 .qc-paging-prev {
     border-right-width: 0;
diff --git a/webapp/TargetedMS/js/QCTrendPlotPanel.js b/webapp/TargetedMS/js/QCTrendPlotPanel.js
index 55ae8f4e2..5aed7c05f 100644
--- a/webapp/TargetedMS/js/QCTrendPlotPanel.js
+++ b/webapp/TargetedMS/js/QCTrendPlotPanel.js
@@ -1020,8 +1020,8 @@ Ext4.define('LABKEY.targetedms.QCTrendPlotPanel', {
                 columns: 2,
                 vertical: false,
                 items: [
-                    { boxLabel: 'per replicate', id: 'x-axis-grouping-replicate', name: 'xAxisGrouping', inputValue: 'replicate', checked: this.groupedX === false },
-                    { boxLabel: 'per date', id: 'x-axis-grouping-date', name: 'xAxisGrouping', inputValue: 'date', checked: this.groupedX === true }
+                    { boxLabel: 'per replicate', id: 'x-axis-grouping-replicate', name: 'xAxisGrouping', inputValue: 'replicate', checked: this.groupedX === false, listeners: { afterrender: function(r) { r.inputEl.set({'aria-label': 'X-axis grouping: per replicate'}); } } },
+                    { boxLabel: 'per date', id: 'x-axis-grouping-date', name: 'xAxisGrouping', inputValue: 'date', checked: this.groupedX === true, listeners: { afterrender: function(r) { r.inputEl.set({'aria-label': 'X-axis grouping: per date'}); } } }
                 ],
                 listeners: {
                     scope: this,
@@ -1050,8 +1050,8 @@ Ext4.define('LABKEY.targetedms.QCTrendPlotPanel', {
                 columns: 2,
                 vertical: false,
                 items: [
-                    { boxLabel: 'per precursor', name: 'showPlots', id: 'plots-per-precursor', inputValue: 'per-precursor', checked: this.singlePlot === false },
-                    { boxLabel: 'combined', name: 'showPlots', id: 'plots-combined', inputValue: 'combined', checked: this.singlePlot === true }
+                    { boxLabel: 'per precursor', name: 'showPlots', id: 'plots-per-precursor', inputValue: 'per-precursor', checked: this.singlePlot === false, listeners: { afterrender: function(r) { r.inputEl.set({'aria-label': 'Plots: per precursor'}); } } },
+                    { boxLabel: 'combined', name: 'showPlots', id: 'plots-combined', inputValue: 'combined', checked: this.singlePlot === true, listeners: { afterrender: function(r) { r.inputEl.set({'aria-label': 'Plots: combined'}); } } }
                 ],
                 listeners: {
                     scope: this,
@@ -1081,8 +1081,8 @@ Ext4.define('LABKEY.targetedms.QCTrendPlotPanel', {
                 columns: 2,
                 vertical: false,
                 items: [
-                    { boxLabel: 'show', id: 'excluded-replicates-show', name: 'excludedSamples', inputValue: 'show', checked: this.showExcluded === true },
-                    { boxLabel: 'hide', id: 'excluded-replicates-hide', name: 'excludedSamples', inputValue: 'hide', checked: this.showExcluded === false }
+                    { boxLabel: 'show', id: 'excluded-replicates-show', name: 'excludedSamples', inputValue: 'show', checked: this.showExcluded === true, listeners: { afterrender: function(r) { r.inputEl.set({'aria-label': 'Excluded replicates: show'}); } } },
+                    { boxLabel: 'hide', id: 'excluded-replicates-hide', name: 'excludedSamples', inputValue: 'hide', checked: this.showExcluded === false, listeners: { afterrender: function(r) { r.inputEl.set({'aria-label': 'Excluded replicates: hide'}); } } }
                 ],
                 listeners: {
                     scope: this,
@@ -1110,8 +1110,8 @@ Ext4.define('LABKEY.targetedms.QCTrendPlotPanel', {
                 columns: 2,
                 vertical: false,
                 items: [
-                    { boxLabel: 'show', id: 'excluded-precursors-show', name: 'excludedPrecursors', inputValue: 'show', checked: this.showExcludedPrecursors === true },
-                    { boxLabel: 'hide', id: 'excluded-precursors-hide', name: 'excludedPrecursors', inputValue: 'hide', checked: this.showExcludedPrecursors === false }
+                    { boxLabel: 'show', id: 'excluded-precursors-show', name: 'excludedPrecursors', inputValue: 'show', checked: this.showExcludedPrecursors === true, listeners: { afterrender: function(r) { r.inputEl.set({'aria-label': 'Excluded precursors: show'}); } } },
+                    { boxLabel: 'hide', id: 'excluded-precursors-hide', name: 'excludedPrecursors', inputValue: 'hide', checked: this.showExcludedPrecursors === false, listeners: { afterrender: function(r) { r.inputEl.set({'aria-label': 'Excluded precursors: hide'}); } } }
                 ],
                 listeners: {
                     scope: this,
@@ -1144,8 +1144,8 @@ Ext4.define('LABKEY.targetedms.QCTrendPlotPanel', {
                 columns: 2,
                 vertical: false,
                 items: [
-                    { boxLabel: 'always show', id: 'reference-guide-set-show', name: 'referenceGuideSets', inputValue: 'show', checked: this.showReferenceGS === true },
-                    { boxLabel: 'when in date range', id: 'reference-guide-set-hide', name: 'referenceGuideSets', inputValue: 'hide', checked: this.showReferenceGS === false }
+                    { boxLabel: 'always show', id: 'reference-guide-set-show', name: 'referenceGuideSets', inputValue: 'show', checked: this.showReferenceGS === true, listeners: { afterrender: function(r) { r.inputEl.set({'aria-label': 'Reference guide sets: always show'}); } } },
+                    { boxLabel: 'when in date range', id: 'reference-guide-set-hide', name: 'referenceGuideSets', inputValue: 'hide', checked: this.showReferenceGS === false, listeners: { afterrender: function(r) { r.inputEl.set({'aria-label': 'Reference guide sets: when in date range'}); } } }
                 ],
                 listeners: {
                     scope: this,
@@ -1283,11 +1283,11 @@ Ext4.define('LABKEY.targetedms.QCTrendPlotPanel', {
     getPaginationBtns: function(numOfPrecursors) {
         var btnHtml = '';
 
-        btnHtml += '<span class="qc-paging-prev ' + (this.pagingStartIndex > 0 ? 'qc-paging-icon-enabled' : 'qc-paging-icon-disabled')
-                + '"><i class="fa fa-angle-left"></i></span>';
+        btnHtml += '<button type="button" class="qc-paging-prev ' + (this.pagingStartIndex > 0 ? 'qc-paging-icon-enabled' : 'qc-paging-icon-disabled')
+                + '" aria-label="Previous page"' + (this.pagingStartIndex > 0 ? '' : ' disabled') + '><i class="fa fa-angle-left" aria-hidden="true"></i></button>';
 
-        btnHtml += '<span class="qc-paging-next ' + (this.pagingEndIndex < numOfPrecursors ? 'qc-paging-icon-enabled' : 'qc-paging-icon-disabled')
-                + '"><i class="fa fa-angle-right"></i></span>';
+        btnHtml += '<button type="button" class="qc-paging-next ' + (this.pagingEndIndex < numOfPrecursors ? 'qc-paging-icon-enabled' : 'qc-paging-icon-disabled')
+                + '" aria-label="Next page"' + (this.pagingEndIndex < numOfPrecursors ? '' : ' disabled') + '><i class="fa fa-angle-right" aria-hidden="true"></i></button>';
 
         return btnHtml;
     },