diff --git a/app/phagegap/templates/about/contact.html b/app/phagegap/templates/about/contact.html index 2ed7c7d..30c85bd 100644 --- a/app/phagegap/templates/about/contact.html +++ b/app/phagegap/templates/about/contact.html @@ -1,37 +1,28 @@ -
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Code availability

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- The source code of this project is freely available on GitHub: - Integrative-Transcriptomics/PhageGap - contains the code base for this web application. - Integrative-Transcriptomics/phage_dark_matter - contains the code base for the underlying prediction model. -

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Contact

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- Simon Hackl [simon.hackl(at)uni-tuebingen.de] -
- Integrative Transcriptomics, Institute for Bioinformatics and - Medical Informatics, University Tübingen -
- Sand 14, 72076 Tübingen, Germany -
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For questions or issues, use the project repository or contact the listed maintainer.

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Citation

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If you use this software, please cite it as below:

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Citation

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If you use this software, please cite:

PhageGAP: Prediction of phage protein function using protein language models

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- Simon Hackl, Mona Scheurenbrand, Kay Nieselt, Maik Wolfram-Schauerte -

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- Unpublished. GitHub: - Integrative-Transcriptomics/PhageGap -

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Simon Hackl, Mona Scheurenbrand, Kay Nieselt, Maik Wolfram-Schauerte

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Unpublished software; source code: https://github.com/Integrative-Transcriptomics/PhageGap

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Overview

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Results and terms

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This page explains the main items shown after you run Function Classification.

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Protein embeddings

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Global Embedding Landscape

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  • Reference points: proteins from the built-in reference metadata, grouped by functional category color.
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  • User Data: proteins from your submission.
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  • Click a User Data point: opens linked details (prediction bars, nearest-neighbor alignment, structure, and optional genomic focus).
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  • Nearest-neighbor link: a line is drawn from the selected user protein to its nearest reference protein.
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Prediction model

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Function Prediction values

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  • top1, top2, top3: three ranked predicted labels.
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  • P(top1), P(top2), P(top3): corresponding probabilities.
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  • nearest_neighbor_ID: closest reference protein used for detailed comparison.
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  • nearest_neighbor_distance: distance to that reference in embedding space (smaller means closer).
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Functional classes

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ClassDescription
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Nearest-neighbor views

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  • Sequence Alignment: residue-level comparison between your selected protein and its nearest neighbor.
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  • Structure view: nearest-neighbor 3D structure with alignment-based coloring; available quality values may include mean pLDDT and predicted TM-score.
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Genomic Context

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After GFF upload, CDS features are shown by genomic position and strand.

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  • If a CDS Name matches a submitted protein ID, its block is colored by the predicted category.
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  • Feature tooltips can show ID, locus_tag, position, strand, product, and predicted category.
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Functional categories used in the interface

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Reference proteins are displayed in these top-level categories:

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+ Replication, NA processing, Structural, Assembly, Translation, Anti-Defense, Effectors, Host takeover, Lysis, Lysogeny, AMGs +
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Predicted labels (top1 etc.) are displayed alongside their mapped top-level category in tooltips and charts.

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